3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid, identified by CAS Number 376592-93-7, is an aromatic biphenyl carboxylic acid containing three important functional groups: an amino group, a hydroxy group, and a carboxylic acid group. I regard it primarily as a research and pharmaceutical-intermediate building block rather than as a finished active pharmaceutical ingredient. Its calculated molecular formula is C13H11NO3, and its calculated molecular weight is approximately 229.23 g/mol. For procurement, buyers should confirm identity, assay, impurity profile, physical form, packaging, and intended-use requirements directly with the supplier.
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The chemical name describes the substitution pattern on the biphenyl structure. “Biphenyl” indicates two benzene rings connected by a single carbon-carbon bond, while “carboxylic acid” identifies the -COOH group. The terms “amino” and “hydroxy” indicate -NH2 and -OH substituents, respectively, at the positions specified by the systematic name.
This combination of functional groups gives the compound several possible reaction sites. The carboxylic acid can participate in esterification, amidation, and related coupling chemistry, while the amino group may be used in acylation, diazotization, or other transformations depending on the reaction design. The phenolic hydroxy group can also influence polarity, hydrogen bonding, and downstream protection or derivatization strategies.
| Property | Information |
|---|---|
| Common chemical name | 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid |
| CAS Number | 376592-93-7 |
| Calculated molecular formula | C13H11NO3 |
| Calculated molecular weight | Approximately 229.23 g/mol |
| Chemical class | Aromatic amino-hydroxy carboxylic acid |
The molecular formula and molecular weight shown above are calculated from the stated structure and should be checked against the supplier’s certificate of analysis and analytical testing. I recommend using the CAS Number together with the complete chemical name when requesting quotations, because positional isomers can have similar names but different reactivity and performance. Where available, a structure file or confirmed structural drawing can further reduce ordering risk.
In a synthesis program, this compound can serve as a multifunctional aromatic intermediate. Its three functional groups allow chemists to explore sequential or selective transformations, including formation of amides, esters, heterocyclic products, and other substituted aromatic molecules. The actual suitability depends on reaction conditions, protection strategy, regioselectivity, and the impurity tolerance of the target process.
Because the compound contains both polar and aromatic features, it may be useful when a project requires a rigid biaryl scaffold together with opportunities for further functionalization. However, I would not describe it as suitable for a specific therapeutic application without a defined synthesis route, toxicological assessment, and regulatory evaluation. Its role should therefore be assessed at the intermediate or research-material level.
These are application contexts rather than guaranteed end uses. A buyer should provide the intended reaction, scale, and quality requirements before selecting a grade. If the material will enter a regulated development program, the documentation package should be reviewed by the buyer’s quality and regulatory teams.
Suppliers may offer this type of intermediate in different commercial quantities, packaging formats, and quality levels. A small research quantity may be appropriate for route scouting, whereas process development may require a larger batch supported by batch-specific testing. The exact appearance, assay, water content, residual solvents, and impurity limits should be confirmed rather than assumed from the product name.
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For many synthetic projects, a buyer may initially request a purity target such as 98% or higher by the agreed analytical method. That figure should be treated as a purchasing specification only when it is written into the quotation, specification sheet, and certificate of analysis. HPLC, NMR, LC-MS, water determination, and residual-solvent testing may each provide useful information, but the appropriate panel depends on the application.
| Specification area | Questions for the supplier |
|---|---|
| Identity | Does the batch match CAS 376592-93-7 and the requested structure? |
| Assay and purity | What method is used, and what acceptance limit applies? |
| Impurities | Are positional isomers, starting materials, or reaction by-products controlled? |
| Physical form | Is the material supplied as a solid or powder, and is particle-size information available? |
| Documentation | Can the supplier provide a batch-specific COA and applicable safety documentation? |
| Packaging | Is the packaging compatible with the quantity, transport route, and storage plan? |
When I evaluate a supplier for CAS 376592-93-7, I first compare technical consistency rather than focusing only on the lowest quoted price. The supplier should be able to explain the manufacturing or sourcing route at an appropriate level, identify the analytical methods used, and clarify whether the quoted material is from an available batch or requires production. This information helps distinguish a real supply plan from a catalogue-only listing.
Buyers should also consider the relationship between quantity and quality requirements. A laboratory buyer may prioritize small-quantity availability and rapid documentation, while a process-development buyer may prioritize reproducibility, impurity control, change notification, and scale-up communication. If the compound is part of a multi-step route, even a small variation in impurity profile can affect downstream purification or reaction performance.
Pricing and lead time should be requested against a clear specification. A quote without purity, packaging, delivery term, and validity information is difficult to compare accurately. I also recommend confirming whether the product name, CAS Number, formula, and analytical results are consistent across the quotation, label, COA, and shipping documents.
At Maison Chemical, we support B2B inquiries for 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7 as a chemical manufacturing and supply partner. We can discuss the required quantity, target specification, intended application, packaging preference, and delivery destination before preparing a commercial proposal. This approach allows us to clarify whether the request concerns research quantities, process development, or a more structured supply program.
We can also help buyers organize the technical information needed for internal evaluation, including product identity, available documentation, requested testing, and sample requirements. Any specification, availability, or lead-time statement should be confirmed for the individual inquiry because supply conditions may vary by quantity and production schedule. For regulated or sensitive projects, buyers should review all documentation through their own quality and compliance procedures.
3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7 is a multifunctional aromatic intermediate with a biphenyl core, amino group, hydroxy group, and carboxylic acid group. Its calculated formula is C13H11NO3, and its calculated molecular weight is approximately 229.23 g/mol. These structural features make it potentially relevant to medicinal chemistry, pharmaceutical-intermediate development, and specialty synthesis, but final suitability must be confirmed through route-specific evaluation.
The practical next step is to send Maison Chemical your required quantity, target purity, analytical method, packaging needs, destination, and intended use. We can then review the specification and provide the appropriate availability, documentation, sample, and quotation information. A clear technical request at the beginning is the most reliable way to reduce sourcing uncertainty and determine whether this material fits your project.
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